Baumler Lab is a lab in the Department of Food Science and Nutrition at the University of Minnesota led by Dr. David J. Baumler. Research areas include Microbial Systems Biology, the Food Microbiome, Development of Innovative Food Safety Methods, Antimicrobials, Chili Peppers, and Paleo Systems Biology.

About the Lab

Baumler Lab is a research laboratory in the Department of Food Science and Nutrition at the University of Minnesota led by Assistant Professor David J. Baumler.

The central focus of our research is four main areas that use systems biology and food microbiology methods to:

-Study infectious disease of foodborne pathogens and beneficial microbial flora during interactions with hosts through a combination of experimental and computational methods using genome-scale metabolic models.

-Investigate the fermentation processes of yeast and microorganisms used in the food/beverage industry

-Characterize flavor profiles and antimicrobial properties of chili peppers for use in the food industry and in many fermented items such as cheese, meats, and beverages.

-Infer metabolism of ancient/ancestral microorganisms through a new field called “Paleo Systems Biology,” started by Dr. David J. Baumler.

About the Lab

Baumler Lab is a research laboratory in the Department of Food Science and Nutrition & the Biotechnology Institute at the University of Minnesota led by Assistant Professor David J. Baumler.

The central focus of our research is in areas that use genomics, systems biology, and food microbiology methods to:

-Study infectious disease of foodborne pathogens and beneficial microbial flora during interactions with hosts through a combination of experimental and computational methods using genome-scale metabolic models.

-Genomics of foodborne pathogens

-Microbiome research throughout the food supply chain from farm to fork

-Characterize flavor profiles, antimicrobial properties, and genomics of >500 varieties of chili (chile) peppers for use in the food industry and to improve human health

-New technologies for non-thermal processing of foods

-Worldwide food safety

-Infer metabolism of ancient/ancestral microorganisms through a new field called “Paleo Systems Biology,” started by Dr. David J. Baumler.

Latest Publications

Publications as an Assistant Professor at the University of Minnesota:

1. Variation in photosynthetic parameters among pepper (Capsicum spp.) varieties that vary in indigenous habitatHortScience Journal (in press)

2. Evaluation of Methods for Inoculating Dry Powder Food Ingredients with Salmonella enterica serovar Typhimurium LT2, Enterococcus faecium or Cronobacter sakazakii. Journal of Food Protection (in press)

3. Draft Genome sequence of hyperthermophilic, halotolerant Parageobacillus toebii PW12 isolated from Tattapani hot spring of North West Himalayas. Microbiology Resources Announcement

4. Determination of antimicrobial activity of heirloom Capsicum varieties against numerous human microbial pathogens. Journal of Medicinal Plants Research

5. Sequentially fractionation by organic solvents enhances the antioxidant and antibacterial activity of ethanolic extracts of fruits and leaves of Terminalia bellerica from north Western Himalayas, India. Pharmacognosy Journal

6. Segmented Filamentous Bacteria – metabolism meets immunity. Frontiers in Microbiology

7. Using genome-scale metabolic models to compare serovars of the foodborne pathogen Listeria monocytogenes. PLoS One

8. Draft Genome Sequence of Halobacillus trueperi SS1 isolated from Lunsu, a salt water body of North West Himalayas. Microbiology Resources Announcement

9. Genome‐wide Genotyping of a Novel Mexican Chile Pepper Collection Illuminates the History of Landrace Differentiation after Capsicum annuum L. Domestication. Evolutionary Applications

10. Effects of intense pulsed light on Cronobacter sakazakii inoculated in non-fat dry milk. Journal of Food Engineering

11. Identification of Thermophilic Flavobacterium and Anoxybacillus in Unexplored Tatapani Hotspring of Kishtwar District of Jammu and Kashmir: A North Western Himalayan State. Current Trends in Biotechnology and Pharmacy Journal.

12. 16S rDNA based bacterial Metagenomics Diversity in a water-soil sample of Pangong Tso Lake, a high altitude grass land lake of North West Himalayas. Microbiology Resources Announcement

13. Methanolic extracts of the rhizome of R. emodi act as bioenhancer of synthetic antibiotics against bacteria and fungi and antioxidant potential. Medicinal Plant Research Journal

14. Microbial Risk Analysis of Produce Grown on a Sustainable Chicken Production Farming System. Food Science and Nutrition Technology

15. Vitamin Variation in Capsicum Spp. Provides Opportunities to Improve Nutritional Value of Human Diets. PLoS One journal

16. Predicting essential metabolic genome content of niche-specific enterobacterial human pathogens during simulation of host environments. PLoS One

17. A survey of Escherichia coli O157:H7 virulence factors: The first 25 years and 13 genomes. Advances in Microbiology

18. Antimicrobial properties of chili peppers. J. Infectious Diseases and Therapy

Select publications from the University of Wisconsin-Madison (Below)

Inferring ancient enterobacterial metabolism using ancestral core metabolic models.
BMC Systems Biology journal

Use of comparative genomics for inquiry-based learning to dissect virulence of Escherichia coli O157:H7 and Yersinia pestis.
Cell Biology Education-Life Science Education (CBE-LSE) journal

The Evolution of Metabolic Networks of E. coli.
BMC Systems Biology journal